Any disorder that prevents the normal movement of various biomolecules between different compartments or to the surface of the cell using vesicles. Vesicular trafficking is particularly important for the movement of glycoconjugates and proteins involved in glycosylation from the ER to the Golgi, and disorders of vesicle trafficking may negatively impact multiple glycosylation pathways.
Synonyms:
disorders of vesicular trafficking, disorder of vesicle trafficking, disorders of vesicle trafficking